Issue N# 5 - 2008
Results of alginate and hypertonic solution in wound healing of head and neck cancers
Authors : Diallo BK, Lacher-Fougere S, Baltazart B, Traissac L, Houliat T. (Dakar)
Ref. : Rev Laryngol Otol Rhinol. 2008;129,5:289-292.
Article published in french
Downloadable PDF document french
Introduction: In head and neck cancers, complications such as pharyngostoma, orostoma, or fistula can present following surgery or surgery after irradiation. Objective: To report the results of the association of two sea-derived products (Sinomarin® and Algosteril®) compared to normal saline for the management of healing. Material and Methods: This is retrospective study (1998-2000). Thirty patients were included in group 1 (Sinomarin®-Algosteril®) and 17 patients in group 2 (normal saline). The average age was respectively 60 and 56.2. Patients in both groups presented with advanced head and neck carcinoma (T3-T4) and healing complications. Results: The delay of healing was respectively of 33.53 and 72.94 days. Results were statistically significant (Student T-test P< 0.05). Conclusion: Our results show the efficiency (p< 0.05) of the Sinomarin® Algosteril® association in head and neck cancer healing complications.
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