Issue N# 2 - 2013
CANCER
Prognostic value of sentinel lymph node in Merkel cell carcinoma of the head and neck
Authors : Penicaud M, Cammilleri S, Giorgi R, Taïeb D, Grob JJ, Giovanni A, Dessi P, Fakhry N. (Marseille)
Ref. : Rev Laryngol Otol Rhinol. 2013;134,2:75-79.
Article published in french 
Downloadable PDF document french
Summary :
Introduction: Merkel cell carcinoma (MCC) is a rare neuroendocrine skin tumor. The aim of our study was to analyze the prognosis of patients operated on for CCM and having no lymph node involvement after analysis of sentinel lymph node (SLN). Material and Method: This was a retrospective study of 10 cases of CCM stage I or II who received the SLN technique in our institution between 2003 and 2010. Results: Among the 10 patients, 7 had an identification of at least one SLN, among which the node could be surgically removed in 6 cases. In cases of failure of SLN technique, a neck dissection ± parotidectomy was performed. No lymph node metastasis was found in our series. Mean follow-up was 38 months. The overall survival rate was 100% at 2 years and 50% at 5 years. The Disaese-free survival was 85% at 2 and 5 years. Conclusion: Our results show that the technique of sentinel lymph node is a reliable tool for evaluating nodal status of patients with CCM and that pN0 patients have a good prognosis.
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