Issue N# 4 - 2010
MISCELLANEOUS
Is HIV/AIDS an independent risk factor of chronic rhinosinusitis among Central African patients?
Authors : Nzuzi Kawashi P, Longo-Mbenza B, Matanda Nzanza R, Nge Okwe A, Mbungu Fuele S. (Kinshasa)
Ref. : Rev Laryngol Otol Rhinol. 2010;131,4:247-251.
Article published in french 
Downloadable PDF document french
Summary :
Objectives: To investigate the independent effect of HIV/ AIDS in the genesis of acute or chronic rhinosinusitis. Methods: This case-control study was performed among patients managed for chronic rhinosinusitis between January and April 2009 the ENT and Head and Neck Department General Hospital of Kinshasa, DRCongo. Cases were matched with controls according to gender and age. Logic regression analysis served to identify factors associated with presence of chronic rhinosinusitis. Results: The study population with 108 patients included 81 cases ofrhinosinusitis, 27 controls, 78 females, 30 males, 52 with HIV/AIDS and 56 HIV seronegatives. The mean age was 34±19 years (range 1 year-74 years). Only HIV/AIDS was identified as a significant and independent determinant of presence of chronic rhinosinusitis (OR= 19,6 95% CI 4,3 -88,9; P< 0,0001). Conclusion: Early ENT evaluation and continuous follow-up of HIV-infected patients are suggested. Age upper 20 years and high education attainment were significantly associated with high risk of chronic rhinosinusitis among HIV-infected patients, respectively.
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