2019    N# 1 | 2018    N# 1 | 2 | 3 | 4 | 5 | 2017    N# 1 | 2 | 3 | 4 | 5 | 2016    N# 1 | 2 | 3 | 4 | 5 | 2015    N# 1 | 2 | 3 | 4 | 5 | 2014    N# 1 | 2 | 3 | 4 | 5 | 2013    N# 1 | 2 | 3 | 4 | 5 | 2012    N# 1 | 2 | 3 | 4 | 5 | 2011    N# 1 | 2 | 3 | 4 | 5 | 2010    N# 1 | 2 | 3 | 4 | 5 | 2009    N# 1 | 2 | 3 | 4 | 5 | 2008    N# 1 | 2 | 3 | 4 | 5 | 2007    N# 1 | 2 | 3 | 4 | 5 | 2006    N# 1 | 2 | 3 | 4 | 5 | 2005    N# | 1 | 2 | 3 | 4 | 5 | 2004    N# 1 | 2 | 3 | 4 | 5 | 2003    N# 1 | 2 | 3 | 4 | 5 | 2002    N# 1 | 2 | 3 | 4 | 5 | 2001    N# 1 | 2 | 3 | 4 | 5 | 2000    N# | 1 | 2 | 3 | 4 | 5 | 1999    N# 1 | 2 | 3 | 4 | 5 | 1998    N# 1 | 2 | 3 | 5 | 1997    N# 1 | 2 | 3 | 4 | 5 | 1996    N# 4 | 5 | Click on the number of the review to see the content List of all teaching bulletins CME. Editor reading committee. Instructions for authors Select of books and press articles. News information letter. If you wish to adjust the size of the displayed characters, click in the high menu on "Your account" and choose the desired size.	Contents > Previous page > Article detail Issue N# 1 - 2016 RHINOLOGY Efficacy of nasal irrigation with 2.2% hypertonic seawater in the treatment of chronic rhinosinusitis in adults Authors : Strnad P, Skoupá J, HornÍk P, Cimrová H, Cerná V. (Prague) Ref. : Rev Laryngol Otol Rhinol. 2016;137,1:3-10. Article published in english Downloadable PDF document english Summary : Objective: To evaluate the efficacy and the tolerance of nasal irrigation with 2.2% hypertonic seawater in the treatment of chronic rhinosinusitis (CRS) in adults either used as mono­therapy, or in combination with intranasal corticosteroids. Method: In this prospective, open-label, multicenter controlled trial, 238 patients diagnosed with CRS were randomly assigned to three groups: group 1 with intranasal corticosteroids (steroid), group 2 with nasal irrigation with hypertonic seawater (seawater) and group 3 with a treatment combining intranasal corticosteroids at lower dose and seawater (steroid+seawater). Nasal index score (NIS), patient health status, intranasal corticosteroids intake, tolerance were assessed at baseline, week 2 and 6, and satisfaction at week 6. Results: NIS was significantly improved in group 2 (seawater) and group 3 (steroid+seawater) at week 2 (p< 0.001 in both groups) and week 6 (p< 0.0001 in both groups) compared to group 1 (steroid), along with a significant decrease of intranasal corticosteroids (p < 0.0001). Patient health status improved in group 2 and group 3 at week 2 (p= 0.1040 and p< 0.001 respectively) compa­red to control (steroid), and this improvement was significantly greater in both groups at week 6 compared to steroid group (p< 0.0001). Conclusion: Hypertonic nasal irrigation is an effective treatment for CRS in adults. It significantly improved nasal symptoms and allowed a signi­fi­cant decrease of intranasal corticosteroids use while improving patient health status. Nasal irrigation with 2.2% hypertonic seawater could therefore be considered as first-line treatment for CRS, either as monotherapy or in combination with lower dosage of intranasal corticosteroids. Price : 15.00 €
© Copyright 1999-2023 - Revue de Laryngologie   Réalisation - Hébergement ELIDEE