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  Contents > Previous page > Article detail print Order
o Issue N# 3 - 2017 o

OTOLOGY

Observational study to assess the effect of Audistim® on the quality of life of patients presenting with chronic tinnitus


Authors : Frachet B, Portmann D, Allaert FA. (Paris, Bordeaux, Dijon)

Ref. : Rev Laryngol Otol Rhinol. 2017;138,3:79-85.

Article published in english
Downloadable PDF document english



Summary : Objectives: To evaluate the improvement of symptoms, quali­ty of life, psychological stress and sleep quality of patients suffering from chronic tinnitus after a 3 months intake of Audistim®. Methods: Observational study of Audistim® by ENT doctors in patients consulting them for chronic tinnitus. Evaluation criterion: THI quality of life score, PSQI sleep score, MSP-9 Stress score. Patients were examined at baseline and at 3 months. Results: 314 patients aged 54.1 ± 13.0 years and suffering from tinnitus since 5.8 ± 7.3 years were included in the study. At the end of the 3 months, patients’ quality of life chan­­ged from 44.6 ± 23.4 to 26.7 ± 18.7 corresponding to an impro­vement of 40.1% (< 0.0001), subjects’ stress from 38.5 ± 13.3 to 30.1 ± 10.8 to 3 months corresponding to an improve­ment of 21.8% (<0.0001) and sleep quality of 8.4 ± 4.5 to 5.4 ± 3.2 corresponding to an improvement of 35.7%. Quality of life improvement was significantly correlated with stress impro­vement (r: 0.77 (p< 0.0001) and sleep (r: 0.70 (p< 0.0001). Tinnitus were improved in 70.0% of patients according to doc­tors, and in 69% of them according to the patients themselves. 2.8% of patients experienced adverse events, essentially diges­tive, none of which was judged by doctors as imputable to the intake of Audistim®. Conclusion: The original composition of Audistim® combining several active ingredients used to control tinnitus gives rise to clear improvements in the quality of life, stress and sleep of the patients experiencing tinnitus and provides them satisfaction without the risk of adverse events.


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