Issue N# 4 - 2002
A rare tumor of the parapharyngeal space: myxoid chondrosarcoma.
Authors : I. Bahri, T. Boudawara, A. Sellami, A. Khabi, M. Ghorgel, M. Drira, J. Daoud, R. Jlidi (Sfax)
Ref. : Rev Laryngol Otol Rhinol. 2002;123,4:255-258.
Article published in french
Downloadable PDF document french
Extrasqueletal myxoid chondrosarcoma (EMC) is an uncommon soft tissue malignant tumor, locally agressive with a high incidence of distant metastasis. It has distinctive clinical, immunophenotypic, cytogenetic and ultrastructural features. Most EMC are associated with the translocation t(9;22) (q22;q12). Their occurrence in the parapharyngeal space is extremely rare. Our objective is to discuss the difficulties of the histological diagnosis of EMC and to describe its immunophenotypic, cytogenetic features and clinical behavior. We report a case of a 67 years old woman who presented with a five months history of dysphagia. The oral examination found a mass displacing the posterior and left walls of the pharynx. Surgical resection of the tumor was undertaken. The pathologic examination concluded to the diagnosis of an EMC of the left parapharyngeal space. Now, the patient is receiving an adjuvant radiotherapy.
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