Issue N# 2 - 2015
HEAD AND NECK CARCINOLOGY
Chondrosarcoma of the hyoid bone: Case report and review of the literature
Authors : Amaral D, Zagalo C, Cardina C, Vera-Cruz P. (Lisboa)
Ref. : Rev Laryngol Otol Rhinol. 2015;136,2:77-80.
Article published in english
Downloadable PDF document english
Introduction: Chondrosarcomas are cartilaginous tumors that range from low-grade tumors with low metastatic potential to high-grade aggressive tumors with premature and high metastatic rate. Low-grade types have few karyotype abnormalities and are near-diploid, while high-grade chondrosarcomas originate from complex karyotypes and are aneuploid. The most common karyotype aberrations found include 12q13–15 and 9p21 rearrangements. Here, it is presented a case of chondrosarcoma of the hyoid bone with its image, surgical procedure and pathological correlation as well as a review of the literature. Case presentation: A sixty-three year old man presented with a large cervical mass located at submental level. The CT scan revealed a voluminous and well-limited mass of 5×4×3 cm located in the suprahyoid region. The operative finding revealed a grade 2 chondrosarcoma originating from the hyoid bone. Discussion: Chondrosarcoma of the hyoid bone is a rare pathology, thus making it difficult to diagnose. Fine needle biopsies have high diagnostic accuracy, although correct grading is only obtained 46% of the time. CT scan is the golden standard to characterize tumor extension and origin. Surgical excision is the treatment of choice for chondrosarcoma.
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